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As with most other organ system in the human body, changes and loss of function is normal consequence of the ageing process. This is also true of the endocrine system, specifically the levels of testosterone production from the Leydig cells of the testicle. Accompanying the decrease in testosterone is a decrease in erections which also has a component in decrease in the blood supply to the penis making erection not as frequent and not as rigid compared with a young man’s erectile function.
Today, the man with erectile dysfunction (ED) has available to him a wider variety of treatment options than ever before. For nearly all of these men, a trial with a systemic agent such as sildenafil citrate will be the first option chosen. If this fails or is contraindicated, other pharmacologic treatments such as penile injections or intraurethral medication are available but are less attractive than systemic therapy and may either prove ineffective or be rejected. This review will discuss the
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